The Carden Family

When I met my husband to be, Roger, he informed me that I really shouldn’t get serious with him because he had the worst luck in the world. Because I felt I was extremely lucky, I didn’t listen, and although I am glad I didn’t, I really didn’t expect that our life together would progress as it has.

When Roger was 5 years old he came down with a rare illness, hemolytic uremic syndrome. He was hospitalized for five weeks and in recovery for months. His parents made arrangements for his three brothers and sisters to live with relatives while they tended to his recovery. But he survived, and although he had a difficult time catching up in school, his family came back together.

When Roger was 9, flu passed through the household. Roger didn’t get better, and was hospitalized again with hemolytic uremic syndrome. Uncertain of Roger’s chances to survive a second attack, his father got leave from the Navy to be by his bedside. His mother quit her job and this time neighbors chipped in to take care of his brother’s and sisters. This recovery was longer, lasting almost a year. Roger remembers a time of doctor’s visits and needles.

At the age of 19 Roger tried to follow in the footsteps of his father and older brother and signed up for the Navy. During the physical the doctor found that his blood pressure was high and there was protein in his urine. His application was rejected; he was hospitalized for tests on his kidneys.

Despite these facts, at the age of 28, I had a hard time believing our life would be anything but normal. Roger appeared to be healthy and I believed that we would be a normal two career couple, and raise a family.

About a year after we married, Roger had flu-like symptoms. We had been very active the previous week; I thought Roger was just over tired. On Sunday morning we went to the emergency room; Roger was admitted. Not understanding the nature of the disease, it took the doctors four days to diagnose hemolytic uremic syndrome. This bout ended with Roger in complete renal failure. He left the hospital after about a month with a graft in his arm to facilitate dialysis. The seemingly healthy man I married had lost 20 pounds during his hospital stay and was no longer able to work.

We worked hard to maintain the strict diet required for dialysis patients, and attempted to get on with our lives. Roger was bitter constantly fatigued. I lost my job as a property manager. Unable to survive on Roger’s disability pay, I quickly got a job as a waitress so that I could be flexible to care of my husband.

Despite our vigilance, Roger did not do well on dialysis, and his health continued to decline. Within months he was placed on the waiting list for a kidney transplant.

On Thanksgiving weekend, the call came. A cadaver kidney became available, and Roger checked into the hospital. The transplant was successful, and Roger checked out of the hospital the week before Christmas wearing gloves and a surgical mask to prevent him from contracting illnesses due to his suppressed immune system. Two days later, he checked back in to be treated for rejection. He finally came home on Christmas day. We were 30 just years old.

The recovery was slow, but steady. Roger went back to school and got a degree in Accounting so that he could get a job better suited to his health. He had previously worked in labor intensive positions, but could no longer depend on his strength.

We had our first child 6 years after his transplant, a healthy 10 pound baby boy we named Jack. Twenty months later we had our second child, again a healthy 10 pound baby boy we named Clint. Our family was complete. Roger was employed with the Social Security Administration, I had a good job with a private employer.

Finally, we were as we dreamed, a two career couple raising a family. Our boys were perfect. They were healthy, handsome and smart. Life was finally turning around. Our oldest child took after me in thoughts and actions, and the youngest was the spitting image of Roger, so much so that I asked our pediatrician when we would test kidney function. Hemolytic Uremic Syndrome, I was told, was not hereditary.

But shortly after school started in 2002, Clint came down with a sore throat. He was uncharacteristically lethargic so I took him to his pediatrician. A strep culture was negative and we were sent home with a diagnosis of a virus.

By Sunday of that week, Clint had not improved. He had been throwing up and I was concerned he was becoming dehydrated. I forced him to drink liquids, which he would throw up within minutes. On Sunday night I watched Clint urinate, and the words of Roger’s mother echoed in my mind, “Roger’s urine was the color of Coca Cola.” Clint’s urine looked like Coke too. I was terrified.

 

 

On Monday morning, we went to the emergency room. After the doctor drew blood, Clint laid very still on the hospital bed. “Mommy, he said- is heaven real?” Of course, I replied. “Am I going there now?” he asked. Please dear God no, I screamed in my head. The doctor diagnosed HUS immediately. Roger joined me in the emergency room and sobbed. He fully understood what the doctor’s diagnosis meant. So now we know that HUS is hereditary and that it is recurrent. We are living with two shoes in the air, and if our oldest son also has a tendency, perhaps three shoes in the air getting ready to stamp on our dreams and wishes for the future I had actually gotten used to worrying about Roger, laying in bed and wondering how long it had been since he peed, taking his blood pressure when he had a headache, letting him sleep in when he seemed overly tired. Now I follow Clint into the bathroom, and watch the color of his stream. This morning before going to work I got Clint out of bed so that I could watch him go to the bathroom, because I had had an uneasy feeling in the middle of the night.

I desperately want to get to the bottom of this disease that now affects 50% of my family. I cling to the idea that Roger has had many healthy years between childhood and our late twenties, and I pray to God with all my heart that Clint is able to grow to be the man God intends him to be. I want to believe that medicine has come a long way since the 1960’s when Roger first had his bouts with the disease, and even the 80’s when his transplant surgery was done, but I am disturbed to see the treatment is remarkably similar now to when Roger was 5!!! With medical science and technology so advanced that some day we can clone humans, why does the treatment for HUS remain only supportive??

And when I watch Clint wrestle with his older brother, and I want to forget about HUS - I can’t because I think of Ryan Still and Nathan Bierman, and all the other kids I’ve come to know through the Foundation. And then I think of future children, including Jack and Clint’s children, and the devastation that this disease wreaks on entire families. The injustice of our having not progressed to the point of actual treatment of the disease cannot continue.

 We MUST find a cure for this tragic disease.

 

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